Theories of aging, including the Telomere theory, oxidative stress and calorie restriction theories in regards to cell senescence

The study of aging has received much attention in past decades. As the cliché goes, death is as inevitable as taxes, but scientists believe they might know why. No elan possibleness has been deemed the cause of aging; rather there nuclear number 18 many theories from a number of disciplines that overlap. If this is the baptistry there mustiness be a way to stickup aging, thereby change magnitude lifespan. Three of the more promulgated theories are the telomere, aerobic breed and calorie restriction theories which in all have supporting evidence but do not solely explain why jail electric cells senesce. One possibleness embraced by many scientists is the telomere theory. Every chromosome ends in a telomere which shortens all(prenominal) time the cell divides; after tell component parts and considerable telomere loss, the cell undergoes senescence (Steel, 1995). Progeria is a genetic perturbation that results in speed ageing, Allsopp et al (1992) found that progeria patients had shortened telomeres, fortify the argument that telomere trot down results in aging. But there is fancy of a remedy. Studies show that telomerase, an enzyme high in egg and spermatozoan cells, terminate mediate telomere synthesis thus counteracting losses from cell division (Hodes, 1998). However, there may be weaknesses associated with these results.

Lahnert (2005) attempted to break the rule used to measure telomere length because various information from opposite studies are conflicting with some scientists even claiming that telomere shortening was only a myth. Lahnert established that telo mere shortening can be measured but admits ! that the method could be improved. The oxidative emphasize theory proposes that ?programmed? mechanisms, such as telomere shortening, are not the further avertible causes of aging. Free radicals produced through cell metabolism amputate cellular function causing injury (Sharma & Kaur, 2006); this is what is referred to as oxidative stress. Mostly free radicals are derived from oxygen and... If you essential to survive a full essay, order it on our website: OrderCustomPaper.com

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